REMOVAL OF LIVER CANCER

Removal of Liver Cancer

Removal of Liver Cancer is an article that aims to give you all the information you do not know about the removal of liver cancer and more. We kindly shared the main headings with you;

What is liver cancer?

Liver cancer is a potentially lethal disease and one of the tumors that is spreading the fastest in the US. There are two types of liver cancer: primary and secondary. Your liver develops primary carcinoma. Secondary cancer, which starts elsewhere in your body, spreads to your liver. This page gives an overview of primary liver cancer. Medical practitioners can treat liver cancer more successfully in its early stages, just like they can many other types of cancer. Compared to many other cancer types, medical professionals have a good understanding of liver cancer. To diagnose and treat primary liver cancer as soon as possible, medical professionals are determined to identify those who may be more susceptible.

What is the main cause of liver cancer?

When something modifies the DNA of healthy liver cells, liver cancer results. The genes that instruct our cells on how to operate are carried by DNA. Genes that control when cells divide, grow, and die are present in every human. Oncogenes, for instance, promote cell division and growth. Tumor suppressor genes are other genes that keep an eye on cell activity, preventing abnormally high cell division and ensuring that cells die when they should. Our cells receive updated instructions when our DNA mutates or changes. Mutations in the DNA cause oncogenes and/or tumor suppressor genes to become active in HCC. Research indicates that over 50% of instances of hepatitis C virus (HCV) and hepatitis B virus (HBV)-related cirrhosis are associated with HCC. These viruses alter the DNA of the liver cells they infect, transforming them from healthy to malignant cells.

REMOVAL OF LIVER CANCER

How liver cancer affects your body?

The largest organ in your body, the liver aids in food digestion. Since no one could survive without their liver, it is also one of the most vital organs. Among the vital functions your liver does are the following:

  • Gathers and purifies the blood that exits your intestines
  • Absorbs nutrients from your intestines and stores them
  • Transforms some nutrients into compounds your body needs to generate tissue or energy
  • Produces bile, a liquid that aids in fat digestion
  • Produces energy by breaking down and storing other nutrients from diet, such as sugar
  • Produces chemicals that aid in blood clotting

What are the types of liver cancer?

Primary liver cancer comes in three different forms:

  • Hepatocellular carcinoma (HCC): Accounting for almost all occurrences of liver cancer, this is the most prevalent type of the disease.
  • Intrahepatic Cancer (IHC): Cholangiocarcinoma, or intrahepatic cancer (IHC), is one type of the disease. IHC is bile duct carcinoma in the liver. Roughly 10% to 20% of all instances of primary liver cancer are represented by it.
  • Angiosarcoma: Approximately 1% of instances of primary liver cancer are of this extremely uncommon form. The lining of your liver’s blood cells is where this cancer starts. (Additionally, angiosarcoma may impact other organs.)

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What are the symptoms of liver cancer?

In the early stages of liver cancer, you may not exhibit any symptoms at all. The symptoms of intrahepatic cholangiocarcinoma (IHC) and hepatocellular carcinoma (HCC) are comparable:

  • A sore spot on the right side of your abdomen, a lump beneath your ribs, or pain close to your right shoulder
  • Jaundice is a condition that results in yellowing of the skin and eyes
  • Unexplained loss of appetite, sickness, or weight loss
  • Feeling weary
  • Urine with a dark hue

How liver cancer is diagnosed?

If your physical examination reveals liver cancer signs and symptoms, your healthcare professional may suspect liver cancer in you. To find out more, they could request the following tests:

  • Blood testing: To determine whether your liver is healthy or damaged, medical professionals may do blood tests for cancer, such as a liver function test, to look at proteins, enzymes, and other substances. They could run an alfa-fetoprotein (AFP) test. Elevated AFP levels could be a sign of liver cancer.
  • Sonography, or ultrasound: This examination creates images of your soft tissue composition. Ultrasound is a tool used by medical professionals to detect liver cancers.
  • Computed tomography (CT) scan: This unique kind of X-ray provides precise images of your liver and tells you about the location and size of liver tumors.
  • Magnetic resonance imaging (MRI): This test uses radio waves, a big magnet, and a computer to create incredibly clear images of your body.
  • Angiogram: This test aids medical professionals in examining the blood arteries in your liver. Your healthcare provider will inject dye into an artery during this procedure to monitor blood vessel activity and check for obstructions.
  • Biopsy: Medical professionals take tissue from the liver to check for cancerous growths. The most trustworthy method of verifying a liver cancer diagnosis is through biopsies.

What are the stages of liver cancer?

Stages of hepatocellular carcinoma encompass the following:

  • Stage I, very early stage, or stage 0: You have a solitary, smaller than 2-centimeter (cm) tumor in your liver. You have a normal bilirubin level according to blood tests.
  • Stage II, early stage, or stage A: One tumor measuring five centimeters or less, or many tumors measuring three centimeters or less, are present. The tumor may have invaded your blood vessels.
  • Stage III, often known as the intermediate stage or stage B: This is characterized by the possibility of multiple tumors or tumors larger than 5 cm. The tumor may have moved to one of your organs, big blood vessels, or lymph nodes.
  • Stage IV/advanced stage/stage C: The cancer has progressed to other bodily parts, including lymph nodes, bones, and lungs.

What operations do removal of liver cancer include?

Partial Hepatectomy

Surgical resection, or the removal of the tumor through surgery, or a liver transplant are the two most effective treatments for liver cancer. Your best chance of recovery will be if all liver cancer has been eliminated. Treatments like radiation or ablation may also be used to treat small liver malignancies. Surgery to remove part of the liver is known as a partial hepatectomy. This procedure is limited to patients with a single tumor that has not spread into blood vessels, good liver function, and sufficient health for surgery. Initially, imaging tests like CT or MRI with angiography are performed to determine whether the cancer can be entirely removed. Even so, there are situations when the intended surgery cannot be completed because the cancer is discovered to be too big or to have spread too far to be removed.

Side Effects and Risks

Only highly qualified and experienced surgeons should do liver resections since these are significant, dangerous surgeries. Surgeons must take enough liver to attempt to remove all of the cancer while still leaving enough liver intact for the liver to function because patients with liver cancer typically have other liver issues in addition to the cancer.

  • Bleeding: The liver undergoes extensive blood flow, therefore bleeding following surgery is a serious risk. Furthermore, the liver typically produces compounds that support blood clots. Potential bleeding issues may arise from liver damage, both before and after the operation.
  • Virus Infection
  • Anesthesia-related complications
  • Clots of blood
  • Pneumonia
  • New liver cancer: There is a chance that a new liver cancer will arise later since the condition that caused the original liver cancer is still present in the remaining liver.

 

Liver Transplant

For some patients with liver cancer, a liver transplant may be the best course of action when one becomes available. For patients whose tumors cannot be surgically removed due to their location or because their liver is too sick for them to bear having a portion of it removed, liver transplants may be a possibility. Patients with tiny tumors (one less than 5 cm in diameter or two to three no more than 3 cm) that have not spread into surrounding blood arteries are typically treated with transplants. Rarely, patients with resectable cancers—those that can be removed—may also have this option.

Side Effects and Risks

Similar to a partial hepatectomy, a liver transplant is a significant procedure that carries significant risks and needs to be performed by qualified medical professionals. Potential dangers consist of,

  • Bleeding
  • Infection: Immunosuppressive medications are administered to recipients of liver transplants to stop their bodies from rejecting the new organ. There are dangers and adverse effects associated with these medications, including the possibility of developing serious infections. These medications may also accelerate the growth of any liver cancer that has spread outside of the liver by suppressing the immune system. Certain medications intended to stop rejection can also impair the kidneys and bones, increase blood pressure, cholesterol, and diabetes, and possibly start a new malignancy.
  • Clots of blood
  • Anesthesia-related complications
  • Rejection of new liver: Blood tests are performed regularly following a liver transplant to monitor for indications that the body is rejecting the new liver. Occasionally, liver biopsies are also performed to determine whether rejection is occurring and whether medication modifications are necessary to stop rejection.

Why choose Turkey for removal of liver cancer?

Choosing Turkey for the removal of liver cancer can be based on several factors:

  • Medical Expertise: Turkey has several world-class hospitals and medical facilities equipped with advanced technology and skilled medical professionals specializing in liver cancer treatment. Many Turkish doctors are renowned for their expertise in liver surgery and oncology.
  • Cost-effectiveness: Medical treatments in Turkey can be more affordable compared to Western countries or other developed nations. This makes it an attractive option for individuals seeking high-quality medical care at a lower cost.
  • Advanced Technology: Turkish hospitals often invest in cutting-edge medical technology and equipment, including robotic-assisted surgery systems and advanced imaging techniques, which can improve surgical outcomes and recovery times for liver cancer patients.
  • Comprehensive Treatment Options: Turkey offers a wide range of treatment options for liver cancer, including surgery, chemotherapy, radiotherapy, and targeted therapies. Patients can receive personalized treatment plans tailored to their specific needs and medical conditions.

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